Graft-versus-host disease physical examination
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Graft-versus-host disease |
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Differentiating Graft-versus-host disease from other Diseases |
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Graft-versus-host disease physical examination On the Web |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Shyam Patel [2]
Overview
The physical exam for GvHD focuses on the organ involved, including the skin, liver, and GI tract.
Physical Examination
- Skin: Exam findings include erythema, maculopapular rash, and hyperpigmentation.[1] Lichen planus-like lesions have been observed in skin GvHD.[1]
- Liver: Exam findings include jaundice, pruritis, leg swelling, tenderness in the right upper quadrant of the abdomen, bleeding from coagulopathy. The classic physical exam findings are suggestive of cholestatic hepatitis.[1]
- GI tract: Exam findings include abdominal tenderness, diarrhea, hyperactive or hypoactive bowel sounds.
References
- ↑ 1.0 1.1 1.2 Socié G, Ritz J (2014). "Current issues in chronic graft-versus-host disease". Blood. 124 (3): 374–84. doi:10.1182/blood-2014-01-514752. PMC 4102710. PMID 24914139.