Prolactinoma causes

Prolactinoma Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Anmol Pitliya, M.B.B.S. M.D.[2], Faizan Sheraz, M.D. [3]

Overview

There are no established causes for prolactinoma. Most cases of prolactinoma are sporadic.

Causes

There are no established causes for prolactinoma. Most cases of prolactinoma are sporadic. Prolactinoma may occur in approximately 30% of Multiple endocrine neoplasia type 1.It may also occur with Carney complex or McCune-Albright syndrome.

Common causes

• Sporadic
• Hereditary causes:
  • Multiple endocrine neoplasia type 1 (MEN 1)

Less Common/Rare causes

• Hereditary causes:
  • A minority of prolactinoma are associated with:
    1. Carney complex
    2. McCune-Albright Syndrome
    3. Isolated familial pituitary adenoma