Prolactinoma epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: , Anmol Pitliya, M.B.B.S. M.D.[2], Faizan Sheraz, M.D. [3]

Overview

The prevalence of prolactinoma in age group <20 years is 100 per 1,000,000 individuals worldwide.[1]

Prolactinoma most commomly affects age group 20 to 50 years.

Prolactinoma is more common in females than males in age group 20 to 50 years. Frequency becomes similar after age 50 years.

Epidemiology and Demographics

Prevalence

  • The prevalence of prolactinoma in age group <20 years is 100 per 1,000,000 individuals worldwide.[1]
  • Clinically significant pituitary tumors affect the health of approximately 14 out of 100,000 people in United States.
  • Some growth hormone producing tumors also co-secrete prolactin.
  • Microprolactinoma are much more common than macroprolactinoma.

Age

  • Prolactinoma commonly affects individuals of age 20 to 50 years.[1][2]
  • Prolactinoma occur less commonly in age <20 years.

Gender

  • Females usually have microprolactinoma whereas male usually have macroadenoma.
  • Gender wise frequency of prolactinoma depends on age of individual:
    • Age group - 20 to 50 years
      • Females are more commonly affected by prolactinoma than male. The female to male ratio is approximately 10:1.[1]
    • Age group >50 years
      • The frequency of prolactinoma is similar in individuals above 50 years of age.[2]


References

  1. 1.0 1.1 1.2 1.3 Ciccarelli A, Daly AF, Beckers A (2005). "The epidemiology of prolactinomas". Pituitary. 8 (1): 3–6. doi:10.1007/s11102-005-5079-0. PMID 16411062.
  2. 2.0 2.1 Mindermann T, Wilson CB (1994). "Age-related and gender-related occurrence of pituitary adenomas". Clin Endocrinol (Oxf). 41 (3): 359–64. PMID 7893282.

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