Growth hormone deficiency classification

Growth hormone deficiency Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Classification

Growth hormone deficiency can be classified by nature into:

• Congenital: infants may show symptoms from the first day but some patients wait until 6 months to show symptoms. Hypoglycemia, neonatal growth failure, neonatal jaundice, and asphyxia are common in these cases. The combination of GHD with gonadotropin deficiency can cause microphallus, cryptorchidism, and severe hypoglycemia.

• Acquired: it may first appear in children or adults. Children with GHD present with severe growth failure, delayed bone age, delayed puberty, immature face with an underdeveloped nasal bridge, frontal bossing, sparse hair growth, and infantile fat distribution.