Delayed puberty classification
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Eiman Ghaffarpasand, M.D. [2]
Overview
Delayed puberty is almost always due to physiologic exaggerated prolongation of puberty timing in boys, a condition called "constitutional delay of growth and puberty (CDGP)". But the disease may sometimes has another pathophysiologies, such as hypergonadotropic hypogonadism, permanent hypogonadotropic hypogonadism, and functional hypogonadotropic hypogonadism.
Classification
Delayed puberty is almost always due to physiologic exaggerated prolongation of puberty timing in boys, a condition called "constitutional delay of growth and puberty (CDGP)". Delayed puberty may sometimes has another pathophysiologies, however, the CDGP is the most common cause of delayed puberty in both boys and girls. The main classification of delayed puberty is as following:[1]
| Delayed puberty classification | |||||||||||||||||||||||||||||||||||||||||||||||||
| LH, FSH, and GnRH measurement | |||||||||||||||||||||||||||||||||||||||||||||||||
| Normal | Abnormal | ||||||||||||||||||||||||||||||||||||||||||||||||
| constitutional delay of growth and puberty (CDGP) | LH and FSH decreased GnRH increased | LH and FSH decreased GnRH decreased | LH and FSH decreased GnRH decreased (transient) | ||||||||||||||||||||||||||||||||||||||||||||||
| Hypergonadotropic hypogonadism | Permanent hypogonadotropic hypogonadism | Functional hypogonadotropic hypogonadism | |||||||||||||||||||||||||||||||||||||||||||||||
References
- ↑ Palmert, Mark R.; Dunkel, Leo (2012). "Delayed Puberty". New England Journal of Medicine. 366 (5): 443–453. doi:10.1056/NEJMcp1109290. ISSN 0028-4793.