Incidentaloma screening

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Incidentaloma Microchapters

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Differentiating Incidentaloma from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

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Risk calculators and risk factors for Incidentaloma screening

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

According to the [guideline name], screening for [disease name] is not recommended.

Screening

  • According to the European Society of Endocrinology Clinical Practice Guideline, screening for adrenal incidentaloma includes:

Indications for adrenal incidentaloma screening

  • Patients with possible autonomous cortisol secretion or autonomous cortisol secretion for hypertension and type 2 diabetes mellitus.
  • Patients with asymptomatic vertebral fractures.
  • Screening imaging in patients with a hereditary syndrome leading to adrenal tumors.
  • Family screening with 1 mg dexamethasone test can be considered in cases of bilateral macronodular hyperplasia, especially in younger patients.

Screening measures

Disease Laboratory tests
Pheochromocytoma 24-hour urine:

Fractionated

metanephrines

Fractionated

catecholamines

Blood:

Fractionated

metanephrines

Cushing's

syndrome

For patients with

symptoms of Cushing's

syndrome:

24-hour urinary free

cortisol

For patients lacking

symptoms of Cushing's

syndrome:

1 mg overnight

dexamethasone

suppression test

Primary

aldosteronism

Plasma aldosterone

concentration, plasma

renin activity

References

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