Hirsutism differential diagnosis
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: ;Ogheneochuko Ajari, MB.BS, MS [2]
Overview
The diagnosis of hirsutism requires the exclusion of related disorders with peripheral androgen activity. Hirsutism starts shortly after puberty with a slow course and progression.
Differential Diagnosis
- Adrenal Tumors
- Ovarian Tumors
- Congenital Adrenal Hyperplasia
- Exogenous Androgens
- Cushing Syndrome
- Idiopathic Hirsutism
- Polycystic Ovary Disease[1]
Diagnosis | Incidence | Onset | Common symptom |
❑ Polycystic ovary syndrome ❑ Congenital adrenal hyperplasia ❑ Ovarian and androgen secreting tumors ❑ Drug induced |
❑ 70-85% ❑ 5-15% ❑ 1-8% ❑ 0.3-0.1%
|
❑ PCOS insidious ❑ Idiopathic hirsutism Insidious
❑ HAIRAN syndrome insidious |
❑ Irregular menses, hyperandrogenism, polycystic ovary
❑ Total testosterone > 200ng and does not respond to treatment ❑ Related to medications (steroids, danazol etc) ❑ Subset of PCOS with insulin resistance and acanthosis nigricans |