Acute liver failure risk factors
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief:
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Overview
Certain conditions can put a person at risk for developing acute liver failure. These include having certain infections, vascular disorders, autoimmune conditions, metabolic diseases, and primary cancers or malignancies.
Risk Factors
Risk factors in the development of acute liver failure include:
- Drug-related hepatotoxicity and idiosyncratic drug reactions are the most common risk factor in the developed world. The most common drug causing hepatotoxicity is acetaminophen.
- Viral hepatitis is the most common risk factor of acute liver failure in the developing world.
- Old age
- Malnourishment
- Vascular diseases
- Primary liver tumor: Hepatocellular carcinoma
- Secondary liver tumor: Extensive hepatic metastases or infiltration from breast cancer, lung cancer, melanoma, lymphoma, leukemia.
- Long-term lcohol consumption
- Immunocompromised state
- Other systemic diseases