OR51E2

Olfactory receptor, family 51, subfamily E, member 2
Identifiers
Symbols	OR51E2 ; OR51E3P; OR52A2; PSGR
External IDs	Template:MGI HomoloGene: 23713
Gene ontology Molecular function Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO
RNA expression pattern
File:PBB GE OR51E2 221424 s at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Olfactory receptor, family 51, subfamily E, member 2, also known as OR51E2, is a human gene.

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

• Olfactory receptor

Further reading

• Adams MD, Kerlavage AR, Fleischmann RD; et al. (1995). "Initial assessment of human gene diversity and expression patterns based upon 83 million nucleotides of cDNA sequence". Nature. 377 (6547 Suppl): 3–174. PMID 7566098.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Xu LL, Stackhouse BG, Florence K; et al. (2001). "PSGR, a novel prostate-specific gene with homology to a G protein-coupled receptor, is overexpressed in prostate cancer". Cancer Res. 60 (23): 6568–72. PMID 11118034.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Xia C, Ma W, Wang F; et al. (2001). "Identification of a prostate-specific G-protein coupled receptor in prostate cancer". Oncogene. 20 (41): 5903–7. doi:10.1038/sj.onc.1204803. PMID 11593396.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Yuan TT, Toy P, McClary JA; et al. (2002). "Cloning and genetic characterization of an evolutionarily conserved human olfactory receptor that is differentially expressed across species". Gene. 278 (1–2): 41–51. PMID 11707321.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. PMID 14983052.CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Weng J, Wang J, Cai Y; et al. (2005). "Increased expression of prostate-specific G-protein-coupled receptor in human prostate intraepithelial neoplasia and prostate cancers". Int. J. Cancer. 113 (5): 811–8. doi:10.1002/ijc.20635. PMID 15499628.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Weng J, Ma W, Mitchell D; et al. (2006). "Regulation of human prostate-specific G-protein coupled receptor, PSGR, by two distinct promoters and growth factors". J. Cell. Biochem. 96 (5): 1034–48. doi:10.1002/jcb.20600. PMID 16149059.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Xu LL, Sun C, Petrovics G; et al. (2006). "Quantitative expression profile of PSGR in prostate cancer". Prostate Cancer Prostatic Dis. 9 (1): 56–61. doi:10.1038/sj.pcan.4500836. PMID 16231015.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Wang J, Weng J, Cai Y; et al. (2006). "The prostate-specific G-protein coupled receptors PSGR and PSGR2 are prostate cancer biomarkers that are complementary to alpha-methylacyl-CoA racemase". Prostate. 66 (8): 847–57. doi:10.1002/pros.20389. PMID 16491480.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)

External links

• OR51E2+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.