SULT1A2

Sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
File:PBB Protein SULT1A2 image.jpg PDB rendering based on 1cjm.
Available structures PDB Ortholog search: Template:Homologene2PDBe PDBe, Template:Homologene2uniprot RCSB List of PDB id codes 1cjm​, 1ls6​, 1z28​, 1z29​, 2a3r​, 2d06​
Identifiers
Symbols	SULT1A2 ; HAST4; MGC142287; MGC142289; P-PST; ST1A2; STP2; TSPST2
External IDs	Template:OMIM5 HomoloGene: 88641
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO
RNA expression pattern
File:PBB GE SULT1A2 203615 x at tn.png
File:PBB GE SULT1A2 207122 x at tn.png
File:PBB GE SULT1A2 209607 x at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2, also known as SULT1A2, is a human gene.

Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes one of two phenol sulfotransferases with thermostable enzyme activity. Two alternatively spliced variants that encode the same protein have been described.

Further reading

• Weinshilboum RM, Otterness DM, Aksoy IA; et al. (1997). "Sulfation and sulfotransferases 1: Sulfotransferase molecular biology: cDNAs and genes". FASEB J. 11 (1): 3–14. PMID 9034160.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Windmill KF, Christiansen A, Teusner JT; et al. (1998). "Localisation of aryl sulfotransferase expression in human tissues using hybridisation histochemistry and immunohistochemistry". Chem. Biol. Interact. 109 (1–3): 341–6. PMID 9566757.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Glatt H, Engelke CE, Pabel U; et al. (2000). "Sulfotransferases: genetics and role in toxicology". Toxicol. Lett. 112-113: 341–8. PMID 10720750.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Glatt H (2001). "Sulfotransferases in the bioactivation of xenobiotics". Chem. Biol. Interact. 129 (1–2): 141–70. PMID 11154739.
• Glatt H, Boeing H, Engelke CE; et al. (2001). "Human cytosolic sulphotransferases: genetics, characteristics, toxicological aspects". Mutat. Res. 482 (1–2): 27–40. PMID 11535246.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ozawa S, Nagata K, Shimada M; et al. (1995). "Primary structures and properties of two related forms of aryl sulfotransferases in human liver". Pharmacogenetics. 5 Spec No: S135–40. PMID 7581483.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Yamazoe Y, Ozawa S, Nagata K; et al. (1995). "Characterization and expression of hepatic sulfotransferase involved in the metabolism of N-substituted aryl compounds". Environ. Health Perspect. 102 Suppl 6: 99–103. PMID 7889867.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Yamazoe Y, Nagata K, Ozawa S, Kato R (1994). "Structural similarity and diversity of sulfotransferases". Chem. Biol. Interact. 92 (1–3): 107–17. PMID 8033246.CS1 maint: Multiple names: authors list (link)
• Her C, Raftogianis R, Weinshilboum RM (1996). "Human phenol sulfotransferase STP2 gene: molecular cloning, structural characterization, and chromosomal localization". Genomics. 33 (3): 409–20. doi:10.1006/geno.1996.0216. PMID 8661000.CS1 maint: Multiple names: authors list (link)
• Zhu X, Veronese ME, Iocco P, McManus ME (1996). "cDNA cloning and expression of a new form of human aryl sulfotransferase". Int. J. Biochem. Cell Biol. 28 (5): 565–71. PMID 8697101.CS1 maint: Multiple names: authors list (link)
• Dooley TP, Huang Z (1996). "Genomic organization and DNA sequences of two human phenol sulfotransferase genes (STP1 and STP2) on the short arm of chromosome 16". Biochem. Biophys. Res. Commun. 228 (1): 134–40. doi:10.1006/bbrc.1996.1628. PMID 8912648.
• Gaedigk A, Beatty BG, Grant DM (1997). "Cloning, structural organization, and chromosomal mapping of the human phenol sulfotransferase STP2 gene". Genomics. 40 (2): 242–6. doi:10.1006/geno.1996.4575. PMID 9119390.CS1 maint: Multiple names: authors list (link)
• Harris RM, Waring RH, Kirk CJ, Hughes PJ (2000). "Sulfation of "estrogenic" alkylphenols and 17beta-estradiol by human platelet phenol sulfotransferases". J. Biol. Chem. 275 (1): 159–66. PMID 10617600.CS1 maint: Multiple names: authors list (link)
• Engelke CE, Meinl W, Boeing H, Glatt H (2000). "Association between functional genetic polymorphisms of human sulfotransferases 1A1 and 1A2". Pharmacogenetics. 10 (2): 163–9. PMID 10762004.CS1 maint: Multiple names: authors list (link)
• Carlini EJ, Raftogianis RB, Wood TC; et al. (2001). "Sulfation pharmacogenetics: SULT1A1 and SULT1A2 allele frequencies in Caucasian, Chinese and African-American subjects". Pharmacogenetics. 11 (1): 57–68. PMID 11207031.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)