Small nuclear ribonucleoprotein polypeptide A

Small nuclear ribonucleoprotein polypeptide A
File:PBB Protein SNRPA image.jpg PDB rendering based on 1aud.
Available structures PDB Ortholog search: Template:Homologene2PDBe PDBe, Template:Homologene2uniprot RCSB List of PDB id codes 1aud​, 1cx0​, 1drz​, 1dz5​, 1fht​, 1m5k​, 1m5o​, 1m5p​, 1m5v​, 1nu4​, 1oia​, 1sj3​, 1sj4​, 1sjf​, 1u6b​, 1urn​, 1vbx​, 1vby​, 1vbz​, 1vc0​, 1vc5​, 1vc6​, 1vc7​, 1zzn​, 2nz4​, 2oih​, 2oj3​, 2u1a​
Identifiers
Symbols	SNRPA ; U1A
External IDs	Template:OMIM5 Template:MGI HomoloGene: 3380
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO
RNA expression pattern
File:PBB GE SNRPA 201770 at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Small nuclear ribonucleoprotein polypeptide A, also known as SNRPA, is a human gene.

Further reading

• Schonk D, van Dijk P, Riegmann P; et al. (1991). "Assignment of seven genes to distinct intervals on the midportion of human chromosome 19q surrounding the myotonic dystrophy gene region". Cytogenet. Cell Genet. 54 (1–2): 15–9. PMID 1701111.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Hoffman DW, Query CC, Golden BL; et al. (1991). "RNA-binding domain of the A protein component of the U1 small nuclear ribonucleoprotein analyzed by NMR spectroscopy is structurally similar to ribosomal proteins". Proc. Natl. Acad. Sci. U.S.A. 88 (6): 2495–9. PMID 1826055.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Nelissen RL, Sillekens PT, Beijer RP; et al. (1991). "Structure, chromosomal localization and evolutionary conservation of the gene encoding human U1 snRNP-specific A protein". Gene. 102 (2): 189–96. PMID 1831431.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Jessen TH, Oubridge C, Teo CH; et al. (1991). "Identification of molecular contacts between the U1 A small nuclear ribonucleoprotein and U1 RNA". EMBO J. 10 (11): 3447–56. PMID 1833186.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Nagai K, Oubridge C, Jessen TH; et al. (1991). "Crystal structure of the RNA-binding domain of the U1 small nuclear ribonucleoprotein A.". Nature. 348 (6301): 515–20. doi:10.1038/348515a0. PMID 2147232.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Sillekens PT, Habets WJ, Beijer RP, van Venrooij WJ (1988). "cDNA cloning of the human U1 snRNA-associated A protein: extensive homology between U1 and U2 snRNP-specific proteins". EMBO J. 6 (12): 3841–8. PMID 2962859.CS1 maint: Multiple names: authors list (link)
• Oubridge C, Ito N, Evans PR; et al. (1994). "Crystal structure at 1.92 A resolution of the RNA-binding domain of the U1A spliceosomal protein complexed with an RNA hairpin". Nature. 372 (6505): 432–8. doi:10.1038/372432a0. PMID 7984237.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Howe PW, Nagai K, Neuhaus D, Varani G (1994). "NMR studies of U1 snRNA recognition by the N-terminal RNP domain of the human U1A protein". EMBO J. 13 (16): 3873–81. PMID 8070414.CS1 maint: Multiple names: authors list (link)
• Allain FH, Gubser CC, Howe PW; et al. (1996). "Specificity of ribonucleoprotein interaction determined by RNA folding during complex formulation". Nature. 380 (6575): 646–50. doi:10.1038/380646a0. PMID 8602269.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Avis JM, Allain FH, Howe PW; et al. (1996). "Solution structure of the N-terminal RNP domain of U1A protein: the role of C-terminal residues in structure stability and RNA binding". J. Mol. Biol. 257 (2): 398–411. doi:10.1006/jmbi.1996.0171. PMID 8609632.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Lu J, Hall KB (1997). "Tertiary structure of RBD2 and backbone dynamics of RBD1 and RBD2 of the human U1A protein determined by NMR spectroscopy". Biochemistry. 36 (34): 10393–405. doi:10.1021/bi9709811. PMID 9265619.
• Allain FH, Howe PW, Neuhaus D, Varani G (1997). "Structural basis of the RNA-binding specificity of human U1A protein". EMBO J. 16 (18): 5764–72. doi:10.1093/emboj/16.18.5764. PMID 9312034.CS1 maint: Multiple names: authors list (link)
• Neubauer G, King A, Rappsilber J; et al. (1998). "Mass spectrometry and EST-database searching allows characterization of the multi-protein spliceosome complex". Nat. Genet. 20 (1): 46–50. doi:10.1038/1700. PMID 9731529.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ferré-D'Amaré AR, Zhou K, Doudna JA (1998). "Crystal structure of a hepatitis delta virus ribozyme". Nature. 395 (6702): 567–74. doi:10.1038/26912. PMID 9783582.CS1 maint: Multiple names: authors list (link)
• Lutz CS, Cooke C, O'Connor JP; et al. (1998). "The snRNP-free U1A (SF-A) complex(es): identification of the largest subunit as PSF, the polypyrimidine-tract binding protein-associated splicing factor". RNA. 4 (12): 1493–9. PMID 9848648.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Hetzer M, Mattaj IW (2000). "An ATP-dependent, Ran-independent mechanism for nuclear import of the U1A and U2B" spliceosome proteins". J. Cell Biol. 148 (2): 293–303. PMID 10648562.
• Klein Gunnewiek JM, Hussein RI, van Aarssen Y; et al. (2000). "Fourteen residues of the U1 snRNP-specific U1A protein are required for homodimerization, cooperative RNA binding, and inhibition of polyadenylation". Mol. Cell. Biol. 20 (6): 2209–17. PMID 10688667.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Varani L, Gunderson SI, Mattaj IW; et al. (2000). "The NMR structure of the 38 kDa U1A protein - PIE RNA complex reveals the basis of cooperativity in regulation of polyadenylation by human U1A protein". Nat. Struct. Biol. 7 (4): 329–35. doi:10.1038/74101. PMID 10742179.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ajuh P, Kuster B, Panov K; et al. (2001). "Functional analysis of the human CDC5L complex and identification of its components by mass spectrometry". EMBO J. 19 (23): 6569–81. doi:10.1093/emboj/19.23.6569. PMID 11101529.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Simmons A, Aluvihare V, McMichael A (2001). "Nef triggers a transcriptional program in T cells imitating single-signal T cell activation and inducing HIV virulence mediators". Immunity. 14 (6): 763–77. PMID 11420046.CS1 maint: Multiple names: authors list (link)