Colon polyps classification
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sadaf Sharfaei M.D.[2]
Overview
Colon polyps may be classified into two groups of neoplastic and nonneoplastic. Non-neoplastic polyps consist of inflammatory and hamartomatous polyps. Neoplastic polyps consist of serrated and adenomatous polyps. Adenomatous polyps may be classified into several subtypes based on endoscopic, histologic features and degree of dysplasia. Adenomas may be classified according to endoscopic features into four groups including sessile, pedunculated, flat, or depressed. Adenomas may be classified according to histologic features into three groups including tubular, tubulovillous, and villous.
Classification
- Colon polyps may be classified into several subtypes based on:[1][2][3][4][5]
- Malignancy potentials
- Endoscopic features
- Histologic features
- Degree of dysplasia
- Colon polyps may be classified according to the NBI International Colorectal Endoscopic (NICE) classification into two groups:
| NICE criterion | Type 1 | Type 2 | |
|---|---|---|---|
| Color | Same or lighter background | Darker background | |
| Vessels | None, or isolated lacy vessels coursing across the lesion | Brown vessels surrounding the white center | |
| Surface | Circular pattern with dark or white small spots surrounded by lighter mucosa | ||
| Probable pathology | |||
| Picture |
- Colon polyps may be classified according to malignancy potentials into two large groups:
- Non-neoplastic
- Inflammatory polyps
- Inflammatory pseudopolyps
- Prolapse type inflammatory polyps
- Myoglandular polyps
- Hamartomatous polyps
- Juvenile polyps
- Peutz-Jeghers syndrome
- Cronkhite-Canada syndrome
- Phosphatase and tensin homolog (PTEN) hamartoma tumor syndrome
- Inflammatory polyps
- Neoplastic
- Serrated polyps
- Hyperplastic polyps
- Traditional serrated adenomas
- Sessile serrated polyps
- Serrated polyposis syndrome
- Adenomatous polyps
- Serrated polyps
- Non-neoplastic
- Adenomas may be classified according to endoscopic features into four groups:
- Sessile
- Pedunculated
- Flat
- Depressed
- Adenomas may be classified according to histologic features into three groups:
- Tubular
- Villous
- Tubulovillous
- Adenomas may be classified according to degree of dysplasia into two groups:
- Low-grade dysplasia
- High-grade dysplasia
References
- ↑ Shussman, N.; Wexner, S. D. (2014). "Colorectal polyps and polyposis syndromes". Gastroenterology Report. 2 (1): 1–15. doi:10.1093/gastro/got041. ISSN 2052-0034.
- ↑ Li SC, Burgart L (2007). "Histopathology of serrated adenoma, its variants, and differentiation from conventional adenomatous and hyperplastic polyps". Arch. Pathol. Lab. Med. 131 (3): 440–5. doi:10.1043/1543-2165(2007)131[440:HOSAIV]2.0.CO;2. PMID 17516746.
- ↑ Bonnington, Stewart N (2016). "Surveillance of colonic polyps: Are we getting it right?". World Journal of Gastroenterology. 22 (6): 1925. doi:10.3748/wjg.v22.i6.1925. ISSN 1007-9327.
- ↑ Ponugoti, Prasanna; Lin, Jingmei; Odze, Robert; Snover, Dale; Kahi, Charles; Rex, Douglas K. (2017). "Prevalence of sessile serrated adenoma/polyp in hyperplastic-appearing diminutive rectosigmoid polyps". Gastrointestinal Endoscopy. 85 (3): 622–627. doi:10.1016/j.gie.2016.10.022. ISSN 0016-5107.
- ↑ O'Brien, Michael J. (2007). "Hyperplastic and Serrated Polyps of the Colorectum". Gastroenterology Clinics of North America. 36 (4): 947–968. doi:10.1016/j.gtc.2007.08.007. ISSN 0889-8553.