Liver mass classification

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2]

Overview

Liver mass may be classified according to imaging features (hyperechoic vs. hypoechoic), histopathological origin (benign vs. malignant), and distribution (single/focal/solitary vs. multiple).

Classification

Liver mass may be classified according to imaging features, histopathological origin, size, content, and distribution.

• Imaging features

• Hyperechoic
• Hypoechoic

• Histopathological origin

• Benign
• Malignant

• Distribution

• Single (also known as "solitary" or "focal")
• Multiple

• Content

• Solid
• Cystic

The table below summarizes the classification of common liver masses according to histopathological origin.

Classification of liver mass
Benign	Malignant
Hepatic hemangioma Focal nodular hyperplasia Hepatic adenoma Idiopathic noncirrhotic portal hypertension Nodular regenerative hyperplasia Angiolipoma Biliary cystadenoma Regenerative nodules	Hepatocellular carcinoma Cholangiocarcinoma Metastatic disease Angiosarcoma Cystadenocarcinoma Primary lymphoma

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