Lupus nephritis classification

Lupus nephritis Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Cafer Zorkun, M.D., Ph.D. [2], Raviteja Guddeti, M.B.B.S. [3]

Classification

The World Health Organization has divided lupus nephritis into five classes based on the biopsy.

• Class I is histologically normal and does not show any evidence of disease.
• Class II is based on a finding of mesangial lupus nephritis
• Class III is focal proliferative nephritis
• Class IV is diffuse proliferative nephritis
• Class V is membranous nephritis and is characterized by extreme edema and protein loss.
• Class VI Glomerulosclerosis