Oral cancer other diagnostic studies
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Simrat Sarai, M.D. [2], Sargun Singh Walia M.B.B.S.[3]
Overview
Biopsy of the tumor tissue is diagnostic of oral cancer. Other diagnostic studies for oral cancer include endoscopy, indirect pharyngoscopy, laryngoscopy, exfoliative cytology, barium swallow, chest x-ray and bone scan.
Oral Cancer Other Diagnostic Studies
Biopsy
- Only a biopsy can give a definitive diagnosis of oral cancer.
- The types of biopsies typically used for diagnosing oral cancers are:[1][2]
- Incisional biopsy
- Fine needle aspiration (FNA)
- Sentinel lymph node biopsy
Endoscopy
- Endoscopy is used to examine areas inside the body for the diagnosis, staging and treatment of cancer. Endoscopy is used to:[3][4]
Indirect pharyngoscopy and laryngoscopy
- Indirect pharyngoscopy and laryngoscopy to check for any signs of oral cancer and to examin the back of throat
- People diagnosed with oral cancer are also at increased risk for other head and neck cancers, so a doctor will examin the nasopharynx
Exfoliative cytology
- Exfoliative cytology may be used for diagnosis of oral cancer but some cancers may be missed, or may be confused with abnormal non-cancerous cells.[5][6]
Barium swallow
- A barium swallow test may show any irregularities in the larynx, pharynx, mouth and surrounding areas, and can detect small, early oral tumors.[7]
HPV testing
- For cancers of the throat, biopsy samples are often tested to see if HPV infection is present.
- This information can help predict the probable course of the cancer, as people whose cancers are linked to HPV tend to do better than those whose cancers are not.
Bone scan
- Bone scan may be done to check if there are rapidly dividing cells, such as cancer cells, in the bone (especially mandibular invasion).[8]
Dental Exam
- If radiation is part of the treatment plan for oral cancer, a dental exam beforehand by a prosthodontist is usually recommended.
References
- ↑ Calabrese L, Bruschini R, Ansarin M, Giugliano G, De Cicco C, Ionna F, Paganelli G, Maffini F, Werner JA, Soutar D (December 2006). "Role of sentinel lymph node biopsy in oral cancer". Acta Otorhinolaryngol Ital. 26 (6): 345–9. PMC 2639993. PMID 17633153.
- ↑ Calabrese L, Bruschini R, Ansarin M, Giugliano G, De Cicco C, Ionna F, Paganelli G, Maffini F, Werner JA, Soutar D (December 2006). "Role of sentinel lymph node biopsy in oral cancer". Acta Otorhinolaryngol Ital. 26 (6): 345–9. PMC 2639993. PMID 17633153.
- ↑ Thong PS, Olivo M, Chin WW, Bhuvaneswari R, Mancer K, Soo KC (November 2009). "Clinical application of fluorescence endoscopic imaging using hypericin for the diagnosis of human oral cavity lesions". Br. J. Cancer. 101 (9): 1580–4. doi:10.1038/sj.bjc.6605357. PMC 2778520. PMID 19809432.
- ↑ Muldoon TJ, Roblyer D, Williams MD, Stepanek VM, Richards-Kortum R, Gillenwater AM (March 2012). "Noninvasive imaging of oral neoplasia with a high-resolution fiber-optic microendoscope". Head Neck. 34 (3): 305–12. doi:10.1002/hed.21735. PMC 3078517. PMID 21413101.
- ↑ Bánóczy J (December 1976). "Exfoliative cytologic examinations in the early diagnosis of oral cancer". Int Dent J. 26 (4): 398–404. PMID 1068977.
- ↑ Pérez-Sayánsm M, Somoza-Martín JM, Barros-Angueira F, Reboiras-López MD, Gándara-Vila P, Gándara Rey JM, García-García A (April 2010). "Exfoliative cytology for diagnosing oral cancer". Biotech Histochem. 85 (3): 177–87. doi:10.3109/10520290903162730. PMID 20426699.
- ↑ Raber-Durlacher JE, Brennan MT, Verdonck-de Leeuw IM, Gibson RJ, Eilers JG, Waltimo T, Bots CP, Michelet M, Sollecito TP, Rouleau TS, Sewnaik A, Bensadoun RJ, Fliedner MC, Silverman S, Spijkervet FK (March 2012). "Swallowing dysfunction in cancer patients". Support Care Cancer. 20 (3): 433–43. doi:10.1007/s00520-011-1342-2. PMC 3271214. PMID 22205548.
- ↑ Arya S, Chaukar D, Pai P (July 2012). "Imaging in oral cancers". Indian J Radiol Imaging. 22 (3): 195–208. doi:10.4103/0971-3026.107182. PMC 3624743. PMID 23599568.