Hamman-Rich syndrome causes

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Chandrakala Yannam, MD [2]

Overview

There is no specific etiology (idiopathic), that is responsible for developing acute interstitial pneumonitis.

Causes

Life-threatening Causes

  • Life-threatening causes include conditions which may result in death or permanent disability within 24 hours if left untreated. There are no known life-threatening causes of acute interstitial pneumonitis.

Common Causes

Diffuse alveolar damage causes
Infections[2][3] Viruses: Influenza, Herpes simplex virus, Cytomegalovirus, Adenovirus, Respiratory syncytial virus.

Fungi: Disseminated histoplasmosis, Cryptococcus.

Bacteria: Nontuberculous mycobacterial infection

Connective tissue disorders[4][5] Rheumatoid arthritis

Polymyositis/dermatomyositis

Systemic sclerosis (scleroderma)

Systemic lupus erythematosus

Sjögren syndrome

Mixed connective tissue disease

Anti-Jo-1 tRNA synthetase syndrome

Drugs[6] Amiodarone

Bleomycin

Busulfan

Cocaine

Cyclophosphamide

Nitrofurantoin

Carmustine (BCNU)

Cytosine-arabinoside (Ara-C)

Sodium aurothiomalate

Organ transplantation
Aspiration
Oxygen toxicity[7]

References

  1. Bruminhent J, Yassir S, Pippim J (2011). "Acute interstitial pneumonia (hamman-rich syndrome) as a cause of idiopathic acute respiratory distress syndrome". Case Rep Med. 2011: 628743. doi:10.1155/2011/628743. PMC 3114546. PMID 21687544.
  2. Kao KC, Hu HC, Chang CH, Hung CY, Chiu LC, Li SH, Lin SW, Chuang LP, Wang CW, Li LF, Chen NH, Yang CT, Huang CC, Tsai YH (May 2015). "Diffuse alveolar damage associated mortality in selected acute respiratory distress syndrome patients with open lung biopsy". Crit Care. 19: 228. doi:10.1186/s13054-015-0949-y. PMC 4449559. PMID 25981598.
  3. Kato S, Fujisawa T, Enomoto N, Inui N, Nakamura Y, Suda T (June 2015). "Severe respiratory failure associated with influenza B virus infection". Respirol Case Rep. 3 (2): 61–3. doi:10.1002/rcr2.107. PMC 4469142. PMID 26090113.
  4. Castelino FV, Varga J (2010). "Interstitial lung disease in connective tissue diseases: evolving concepts of pathogenesis and management". Arthritis Res. Ther. 12 (4): 213. doi:10.1186/ar3097. PMC 2945045. PMID 20735863.
  5. Lee HK, Kim DS, Yoo B, Seo JB, Rho JY, Colby TV, Kitaichi M (June 2005). "Histopathologic pattern and clinical features of rheumatoid arthritis-associated interstitial lung disease". Chest. 127 (6): 2019–27. doi:10.1378/chest.127.6.2019. PMID 15947315.
  6. Danson S, Blackhall F, Hulse P, Ranson M (2005). "Interstitial lung disease in lung cancer: separating disease progression from treatment effects". Drug Saf. 28 (2): 103–13. PMID 15691221.
  7. Ciencewicki J, Trivedi S, Kleeberger SR (September 2008). "Oxidants and the pathogenesis of lung diseases". J. Allergy Clin. Immunol. 122 (3): 456–68, quiz 469–70. doi:10.1016/j.jaci.2008.08.004. PMC 2693323. PMID 18774381.

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