Antiphospholipid syndrome epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Feham Tariq, MD [2]

Epidemiology and Demographics

Incidence

• The incidence of antiphospholipid syndrome (APS) is approximately 5 cases per 100,000 persons per year.

Prevalence

• The prevalence of APS is approximately 40-50 cases per 100,000 persons worldwide.

Case-fatality rate/Mortality rate

• The case-fatality rate/mortality rate of catastrophic APS is approximately 50%.

Age

• The commonly affected age groups are young to middle aged adolescents.
• However, APS is also seen in children and elderly age group.

Race

• APS due to systemic lupus erythermatosus(SLE) is more commonly seen in the African American and Hispanic population.

Gender

• Middle aged women are more commonly affected by APS than males.

Region

• There is no particular regional predilection.