Mixed connective tissue disease x ray

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shaghayegh Habibi, M.D.[2]

Overview

An x-ray may be helpful in the diagnosis of complications of mixed connective tissue disease, which include polyarthritis (soft tissue atrophy, calcifications, distal interphalangeal joint erosions, juxta-articular osteoporosis, joint space narrowing, marginal erosions, joint deformities without erosions, and osteonecrosis) and interstitial lung disease (ground−glass opacities, peripheral reticular infiltrates, and small irregular opacities).

An x-ray may be helpful in the diagnosis of complications of mixed connective tissue disease, which include:^[1]^[2]^[3]

Polyarthritis
- Features characteristic of arthrits in systemic sclerosis
  - soft tissue atrophy
  - Calcifications
  - Distal interphalangeal joint erosions
- Features characteristic of arthritis in rheumatoid arthritis
  - Juxta-articular osteoporosis
  - Joint space narrowing
  - Marginal erosions
- Features characteristic of arthritis in systemic lupus erythematosus
  - Joint deformities without erosions
  - osteonecrosis
Interstitial lung disease
- Ground−glass opacities
- Peripheral reticular infiltrates
- Small irregular opacities (predominantly in the bases and middle regions)

↑ Abdel-Magied RA, Lotfi A, AbdelGawad EA (August 2013). "Magnetic resonance imaging versus musculoskeletal ultrasonography in detecting inflammatory arthropathy in systemic sclerosis patients with hand arthralgia". Rheumatol. Int. 33 (8): 1961–6. doi:10.1007/s00296-013-2665-8. PMC 3719002. PMID 23354165.
↑ Gutsche M, Rosen GD, Swigris JJ (September 2012). "Connective Tissue Disease-associated Interstitial Lung Disease: A review". Curr Respir Care Rep. 1: 224–232. doi:10.1007/s13665-012-0028-7. PMC 3486427. PMID 23125954.
↑ Bodolay E, Szekanecz Z, Dévényi K, Galuska L, Csípo I, Vègh J, Garai I, Szegedi G (May 2005). "Evaluation of interstitial lung disease in mixed connective tissue disease (MCTD)". Rheumatology (Oxford). 44 (5): 656–61. doi:10.1093/rheumatology/keh575. PMID 15716315.