Membranoproliferative glomerulonephritis secondary prevention

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief:

Overview

Secondary prevention of strategy is a method to reduce the complication of disease, and one of the most important complication of MPGN is end-stage renal disease (ESRD).

Secondary prevention

Risk factors that can predict the progression of the disease to ESRD are included:

• Proteinuria
• Systemic hypertension
• Progressive decline in GFR

When these risk factors have been seen through the natural history of each individual, secondary prevention strategy have been initiate to reduce the chance of ESRD.

Through secondary prevention, these medication should be taken:

• Angiotensin-converting enzyme (ACE) inhibitors
• Angiotensin-receptor blockers
• Combined ACE inhibition and angiotensin receptor antagonism
• Dietary protein restriction