Hamartoma CT
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2] Vamsikrishna Gunnam M.B.B.S [3]
Overview
CT scan is the imaging modality of choice for the diagnosis of hamartoma. On CT scan, hamartoma is characterized by focal collections of fat, a lesion with a smooth edge, and collections of fat alternating with foci of calcification.
CT
Pulmonary Hamartoma
On computed tomography, common findings of pulmonary hamartoma, include:[1][2][3][4][5][6]
- Isodense or hypodense solid masses
- Heterogeneous contrast enhancement relative to adjacent normal parenchyma
- Presence of fat in a well circumscribed solitary pulmonary nodule which does not demonstrate significant growth
- The fat components may be localized or generalized within the nodule and will typically have a Hounsfield measurement of -40 to -120 HU
- Calcification is typically dispersed in the form of multiple lumps throughout the lesion in a popcorn configuration
Spleen Hamartoma
On computed tomography, spleen hamartoma findings, include:[7]
- Isodense or hypodense solid masses
- Heterogeneous contrast enhancement relative to adjacent normal parenchyma
Renal Hamartoma
On computed tomography, common findings of renal hamartoma, include:[8]
- Lesions involve the cortex and demonstrate macroscopic fat (less than -20 HU)
- Small renal hamartomas volume averaging may make differentiation from a small cyst difficult
- Renal hamartomas are fat-poor
- Calcification is rare
Hypothalamic Hamartoma
On computed tomography, common findings of hypothalamic hamartoma, include:[9]
- Iso-attenuating nodule of soft-tissue
- Calcification is rare
- There is no contrast enhancement
Gallery
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CT scan (CT) shows a well circumcised lesion, with intralesional fat and calcification "popcorn-like appearance" adjacent to the hilum.
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CT scan (CT) shows an isodense solid mass in the inferior pole of the spleen.
References
- ↑ Gaerte SC, Meyer CA, Winer-Muram HT, Tarver RD, Conces DJ (2002). "Fat-containing lesions of the chest". Radiographics. 22 Spec No: S61–78. doi:10.1148/radiographics.22.suppl_1.g02oc08s61. PMID 12376601.
- ↑ Brant WE, Helms CA.(2007) Fundamentals of diagnostic radiology. Lippincott Williams & Wilkins.ISBN:0781765188
- ↑ Siegelman, S S; Khouri, N F; Scott, W W; Leo, F P; Hamper, U M; Fishman, E K; Zerhouni, E A (1986). "Pulmonary hamartoma: CT findings". Radiology. 160 (2): 313–317. doi:10.1148/radiology.160.2.3726106. ISSN 0033-8419.
- ↑ Gaerte, Scott C.; Meyer, Cristopher A.; Winer-Muram, Helen T.; Tarver, Robert D.; Conces, Dewey J. (2002). "Fat-containing Lesions of the Chest". RadioGraphics. 22 (suppl_1): S61–S78. doi:10.1148/radiographics.22.suppl_1.g02oc08s61. ISSN 0271-5333.
- ↑ Gleeson T, Thiessen R, Hannigan A, Murphy D, English JC, Mayo JR (October 2013). "Pulmonary hamartomas: CT pixel analysis for fat attenuation using radiologic-pathologic correlation". J Med Imaging Radiat Oncol. 57 (5): 534–43. doi:10.1111/1754-9485.12083. PMID 24119266.
- ↑ Singh H, Khanna SK, Chandran V, Jetley RK (January 1999). "PULMONARY HAMARTOMA". Med J Armed Forces India. 55 (1): 79–80. doi:10.1016/S0377-1237(17)30328-3. PMC 5531795. PMID 28775580.
- ↑ Soto-Medina CA, Mier-Escurra EA, Treviño-Garza F, Ripa-Galván P (2014). "[Splenic hamartoma. Case report]". Cirugía Y Cirujanos (in Spanish; Castilian). 82 (3): 328–31. PMID 25238476.
- ↑ Eble JN (1998). "Angiomyolipoma of kidney". Seminars in Diagnostic Pathology. 15 (1): 21–40. PMID 9503504.
- ↑ Fenoglio KA, Wu J, Kim do Y, Simeone TA, Coons SW, Rekate H, Rho JM, Kerrigan JF (2007). "Hypothalamic hamartoma: basic mechanisms of intrinsic epileptogenesis". Seminars in Pediatric Neurology. 14 (2): 51–9. doi:10.1016/j.spen.2007.03.002. PMID 17544947.