Paroxysmal nocturnal hemoglobinuria physical examination

Paroxysmal nocturnal hemoglobinuria Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

Patients with [disease name] usually appear [general appearance]. Physical examination of patients with [disease name] is usually remarkable for [finding 1], [finding 2], and [finding 3].

OR

Common physical examination findings of [disease name] include [finding 1], [finding 2], and [finding 3].

OR

The presence of [finding(s)] on physical examination is diagnostic of [disease name].

OR

The presence of [finding(s)] on physical examination is highly suggestive of [disease name].

Physical Examination

Appearance of the Patient

• Patients with paroxysmal nocturnal hemoglobinuria usually appear tired.

Vital Signs

• Fever may be present due to infections

Skin

• Pallor
• Skin ecchymoses
• Skin nodules if it is associated with dermal vein thrombosis

HEENT

• HEENT examination of patients with paroxysmal nocturnal hemoglobinuria is usually normal.

Neck

• Neck examination of patients with paroxysmal nocturnal hemoglobinuria is usually normal.

Lungs

• Pulmonary examination of patients with paroxysmal nocturnal hemoglobinuria is usually normal.

Heart

• Cardiovascular examination of patients with paroxysmal nocturnal hemoglobinuria is usually normal.

Abdomen

• Abdominal distention if associated with budd chiari syndrome
• Hepatomegaly
• splenomegaly

Genitourinary

• Genitourinary examination of patients with paroxysmal nocturnal hemoglobinuria is usually normal.