Hairy cell leukemia history and symptoms
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Haytham Allaham, M.D. [2]
Overview
A positive history of splenomegaly or cytopenias is suggestive of hairy cell leukemia. The most common symptoms of hairy cell leukemia include weakness, fatigue, gingival bleeding, epistaxis and menorrhagia.
History
- When evaluating a patient for hairy cell leukemia, you should take a detailed history of the presenting symptom (duration, onset, progression), other associated symptoms, and a thorough medication review. Other specific areas of focus when obtaining the history are outlined below:[1]
- Review occupational history related to sawdust exposure
- Review any exposure to radiations
- Review any exposure to herbicides or diesel
Symptoms
- Symptoms of hairy cell leukemia include:
- Fever
- Night sweats
- Fatigue
- Easy bruising or bleeding
- Generalized weakness
- Weight loss
- Recurrent infections
- Early satiety
References
- ↑ "How I diagnose and manage individuals at risk for inherited myeloid malignancies". Blood. 128 (14): 1800–1813. 2016. doi:10.1182/blood-2016-05-670240. ISSN 0006-4971.