Blue rubber bleb nevus syndrome historical perspective
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Blue rubber bleb nevus syndrome which is also known as BRBNS is a rare condition in which blood vessels do not develop normally especially in the gastrointestinal area. BRBNS shows characteristic blebs that are fluid-filled blisters as visible and well rounded lesions (nevus) .
Historical Perspective
It was first described by Gascoyen in 1860. In 1958 William Bennett Bean described the lesions further and came up with the term BRBNS, chosen because the 'cutaneous hemangiomas have the look and feel of rubber nipples'.