Mantle cell lymphoma physical examination

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: [[Akram}} Sowminya Arikapudi, M.B,B.S. [2]

Overview

Common physical examination findings of mantle cell lymphoma include fever, rash, splenomegaly, hepatomegaly, peripheral lymphadenopathy, and central lymphadenopathy.

Physical Examination

Temperature

Fever is often present.^[1]

Skin

Rash ^[2]

Neck

Cervical lymphadenopathy^[3]

Thorax

Thoracic masses suggestive of central lymphadenopathy^[4]

Chest tenderness

Abdomen

Abdominal masses suggestive of central lymphadenopathy
Splenomegaly^[5]
Hepatomegaly
Abdominal tenderness

Extremities

Peripheral lymphadenopathy^[6]
Bone tenderness^[7]

References

↑ Arati A. Inamdar, Andre Goy, Nehad M. Ayoub, Christen Attia, Lucia Oton, Varun Taruvai, Mark Costales, Yu-Ting Lin, Andrew Pecora & K. Stephen Suh (2016). "Mantle cell lymphoma in the era of precision medicine-diagnosis, biomarkers and therapeutic agents". Oncotarget. 7 (30): 48692–48731. doi:10.18632/oncotarget.8961. PMID 27119356. Unknown parameter |month= ignored (help)
↑ A. Pawarode, M. R. Baer, S. Padmanabhan, P. K. Wallace, M. Barcos, S. N. J. Sait, A. W. Block, M. Wetzler & M. Battiwalla (2005). "Simultaneous presentation of acute monoblastic leukemia and mantle cell lymphoma: case report and review of the literature". Leukemia & lymphoma. 46 (12): 1813–1818. doi:10.1080/10428190500244258. PMID 16263586. Unknown parameter |month= ignored (help)
↑ Julie M. Vose (2017). "Mantle cell lymphoma: 2017 update on diagnosis, risk-stratification, and clinical management". American journal of hematology. 92 (8): 806–813. doi:10.1002/ajh.24797. PMID 28699667. Unknown parameter |month= ignored (help)
↑ Julie M. Vose (2017). "Mantle cell lymphoma: 2017 update on diagnosis, risk-stratification, and clinical management". American journal of hematology. 92 (8): 806–813. doi:10.1002/ajh.24797. PMID 28699667. Unknown parameter |month= ignored (help)
↑ S. Pittaluga, G. Verhoef, A. Criel, I. Wlodarska, J. Dierlamm, C. Mecucci, H. Van den Berghe & C. De Wolf-Peeters (1996). ""Small" B-cell non-Hodgkin's lymphomas with splenomegaly at presentation are either mantle cell lymphoma or marginal zone cell lymphoma. A study based on histology, cytology, immunohistochemistry, and cytogenetic analysis". The American journal of surgical pathology. 20 (2): 211–223. PMID 8554111. Unknown parameter |month= ignored (help)
↑ Julie M. Vose (2017). "Mantle cell lymphoma: 2017 update on diagnosis, risk-stratification, and clinical management". American journal of hematology. 92 (8): 806–813. doi:10.1002/ajh.24797. PMID 28699667. Unknown parameter |month= ignored (help)
↑ Peng Yang, Jun Lin, Hao Liu, Hao Shen & Hui-Lin Yang (2017). "Primary bone mantle cell lymphomas with multiple vertebral compression fractures: A case report". Oncology letters. 13 (3): 1288–1292. doi:10.3892/ol.2017.5553. PMID 28454248. Unknown parameter |month= ignored (help)

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[1] Arati A. Inamdar, Andre Goy, Nehad M. Ayoub, Christen Attia, Lucia Oton, Varun Taruvai, Mark Costales, Yu-Ting Lin, Andrew Pecora & K. Stephen Suh (2016). "Mantle cell lymphoma in the era of precision medicine-diagnosis, biomarkers and therapeutic agents". Oncotarget. 7 (30): 48692–48731. doi:10.18632/oncotarget.8961. PMID 27119356. Unknown parameter |month= ignored (help)

[2] A. Pawarode, M. R. Baer, S. Padmanabhan, P. K. Wallace, M. Barcos, S. N. J. Sait, A. W. Block, M. Wetzler & M. Battiwalla (2005). "Simultaneous presentation of acute monoblastic leukemia and mantle cell lymphoma: case report and review of the literature". Leukemia & lymphoma. 46 (12): 1813–1818. doi:10.1080/10428190500244258. PMID 16263586. Unknown parameter |month= ignored (help)

[3] Julie M. Vose (2017). "Mantle cell lymphoma: 2017 update on diagnosis, risk-stratification, and clinical management". American journal of hematology. 92 (8): 806–813. doi:10.1002/ajh.24797. PMID 28699667. Unknown parameter |month= ignored (help)

[4] Julie M. Vose (2017). "Mantle cell lymphoma: 2017 update on diagnosis, risk-stratification, and clinical management". American journal of hematology. 92 (8): 806–813. doi:10.1002/ajh.24797. PMID 28699667. Unknown parameter |month= ignored (help)

[5] S. Pittaluga, G. Verhoef, A. Criel, I. Wlodarska, J. Dierlamm, C. Mecucci, H. Van den Berghe & C. De Wolf-Peeters (1996). ""Small" B-cell non-Hodgkin's lymphomas with splenomegaly at presentation are either mantle cell lymphoma or marginal zone cell lymphoma. A study based on histology, cytology, immunohistochemistry, and cytogenetic analysis". The American journal of surgical pathology. 20 (2): 211–223. PMID 8554111. Unknown parameter |month= ignored (help)

[6] Julie M. Vose (2017). "Mantle cell lymphoma: 2017 update on diagnosis, risk-stratification, and clinical management". American journal of hematology. 92 (8): 806–813. doi:10.1002/ajh.24797. PMID 28699667. Unknown parameter |month= ignored (help)

[7] Peng Yang, Jun Lin, Hao Liu, Hao Shen & Hui-Lin Yang (2017). "Primary bone mantle cell lymphomas with multiple vertebral compression fractures: A case report". Oncology letters. 13 (3): 1288–1292. doi:10.3892/ol.2017.5553. PMID 28454248. Unknown parameter |month= ignored (help)

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