Thrombosis risk factor modifications
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Shyam Patel [2]
Thrombosis risk factor modifications
In patients with known risk factor(s) of thrombosis formation, risk factor modification may be necessary for preventive purposes. Cost-effect analysis must be taken into account. The prevention process starts by prescribing anti-coagulant and anti-platelet drugs. For instance, the thrombosis prevention pharmacotherapy is routinely administered after major surgical procedures and in patients with hypercoagulability like antiphospholipid syndrome.
Behavioral modifications
- Weight loss: Obesity is a risk factor for thrombosis since adipose tissue produces estrogen, which is pro-thrombotic. Also, obesity contributes to relative immobility and venous stasis, which is a risk factor for thrombosis.
- Smoking cessation: Smoking is a risk factor for thrombosis because it contributes to endothelial damage.
- Exercise: Regular cardiovascular exercise improves blood flow and prevents venous stasis. Exercise is a prophylactic measure against the development of thrombosis.