Pseudomyxoma peritonei history and symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Parminder Dhingra, M.D. [2]

Overview

Symptoms of pseudomyxoma peritonei include abdominal pain, bloating, abdominal distention, weight changes, and infertility.

History

The median age of diagnosis for pseudomyxoma peritonei is 50 years old,it is usually found incidentally in patients undergoing abdominal surgery or imaging for other medical conditions. Due to its non-specific symptoms, most patients are diagnosed with advanced disease. The clinical presentation of the disease is dependent on the progression of the disease. Tumors that originate in appendix typically presents with appendicitis-like symptoms or a pelvic mass due to mucinous deposits and compression on adjacent organs. More advanced disease can present with abdominal distension, bowel obstruction, and ascites. The classic sign termed “jelly belly” is an increase in abdominal girth caused by an accumulation of gelatinous ascites.[1][2]

Symptoms

Symptoms of pseudomyxoma peritonei may include:[2]

  • Abdominal or pelvic pain
  • New-onset hernia[3]
  • Bloating
  • Abdominal distension
  • Weight change
  • Increased abdominal girth.
  • Appendicitis-like symptoms in some cases.[4]
  • Gynecological complaints in females such as menstrual irregularity due to the ovarian deposits of the mucinous tumor.
  • Subcutaneous non tender umbilical nodule have also been reported in rare cases.[5]

References

  1. Dixit A, Robertson JH, Mudan SS, Akle C (April 2007). "Appendiceal mucocoeles and pseudomyxoma peritonei". World J. Gastroenterol. 13 (16): 2381–4. PMC 4147153. PMID 17511043.
  2. 2.0 2.1 Esquivel J, Sugarbaker PH (October 2000). "Clinical presentation of the Pseudomyxoma peritonei syndrome". Br J Surg. 87 (10): 1414–8. doi:10.1046/j.1365-2168.2000.01553.x. PMID 11044169.
  3. Gomes C, Tenreiro N, Marçal A, Moreira H, Pinto B, Avelar P (July 2018). "Pseudomyxoma peritonei presenting as irreducible epigastric hernia". J Surg Case Rep. 2018 (7): rjy148. doi:10.1093/jscr/rjy148. PMC 6044295. PMID 30026907.
  4. Smeenk RM, Verwaal VJ, Zoetmulder FA (February 2007). "[Pseudomyxoma peritonei; a rare tumour that can be treated with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy]". Ned Tijdschr Geneeskd (in Dutch; Flemish). 151 (7): 418–23. PMID 17343142.
  5. Srinivasaiah N, Retnasingam G, Kasarneni R, Slater B (June 2009). "Pseudomyxoma peritonei: a rare presentation as an umbilical nodule". Ir J Med Sci. 178 (2): 219–21. doi:10.1007/s11845-008-0118-2. PMID 18224368.


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