Paget's disease of the breast history and symptoms
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Suveenkrishna Pothuru, M.B,B.S. [2]
Overview
Symptoms of Paget's disease of the breast include itching, redness, thickened skin, and ulceration of the nipple.
History and symptoms
A detailed history documenting the length of time the lesion along with any associated symptoms should be taken. Symptoms of Paget's disease of the breast usually occur in one breast but can present bilaterally. Some patients have two or more or a combination of the below symptoms at presentation, they can also be asymptomatic.Symptoms of Paget's disease of the breast include:[1] [2][3][4][5]
- Puritis or erythema of the nipple and/or areola.
- Flaking, crusting, or thickening of the skin that begins at the nipple and spreads to the areola.
- Erosion or ulceration of the nipple.
- A flattened or inverted nipple.
- Discharge from the nipple that may be yellowish or bloody.
- A palpable breast mass is present in 50% of patients.
References
- ↑ Gaspari, Eleonora; Ricci, Aurora; Liberto, Valeria; Scarano, Angela Lia; Fornari, Maria; Simonetti, Giovanni (2013). "An Unusual Case of Mammary Paget's Disease Diagnosed Using Dynamic Contrast-Enhanced MRI". Case Reports in Radiology. 2013: 1–5. doi:10.1155/2013/206235. ISSN 2090-6862.
- ↑ Paget's disease of the breast. National cancer institute. http://www.cancer.gov/types/breast/paget-breast-fact-sheet
- ↑ Ashikari R, Park K, Huvos AG, Urban JA (September 1970). "Paget's disease of the breast". Cancer. 26 (3): 680–5. PMID 4318756.
- ↑ Tan AR (June 2016). "Cutaneous manifestations of breast cancer". Semin. Oncol. 43 (3): 331–4. doi:10.1053/j.seminoncol.2016.02.030. PMID 27178684.
- ↑ Franceschini G, Masetti R, D'Ugo D, Palumbo F, D'Alba P, Mulè A, Costantini M, Belli P, Picciocchi A (2005). "Synchronous bilateral Paget's disease of the nipple associated with bilateral breast carcinoma". Breast J. 11 (5): 355–6. doi:10.1111/j.1075-122X.2005.21722.x. PMID 16174159.