Nasopharyngeal carcinoma classification
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Nasopharyngeal carcinoma Microchapters |
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Differentiating Nasopharyngeal carcinoma from other Diseases |
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Diagnosis |
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Treatment |
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Case Studies |
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Nasopharyngeal carcinoma classification On the Web |
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American Roentgen Ray Society Images of Nasopharyngeal carcinoma classification |
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Risk calculators and risk factors for Nasopharyngeal carcinoma classification |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Homa Najafi, M.D.[2]Faizan Sheraz, M.D. [3]
Overview
Nasopharyngeal carcinoma may be classified according to microscopic features into 3 subtypes: keratinizing squamous cell carcinoma, nonkeratinizing carcinoma, and undifferentiated type.
Classification
Histologic classification
World Health Classification (2005) for NPC:<ref name= Librepathology>Nasopharyngeal carcinoma
| Type | Histology | Description | EBV | Prevalence | Prognosis |
|---|---|---|---|---|---|
| 1 | Keratinizing SCC | graded poorly-well-differentiated | -ve | bad | |
| 2a | Nonkeratinizing carcinoma, differentiated | well defined cell borders & tumor nest borders | +ve | good | |
| 2b | Nonkeratinizing carcinoma, undifferentiated | sheets/syncytial, vescicular nuclei, prominent nucleoli, pink cytoplasm | most common | ||
| 3 | Basaloid SCC | mimics basal cell carcinoma | least common |