Paget's disease of the breast historical perspective

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Suveenkrishna Pothuru, M.B,B.S. [2]

Overview

Paget's disease of the breast was first discovered by James Paget, a British surgeon and physiologist, in 1874.[1]

Historical Perspective

  • The characteristic erythema and eczematous changes of the nipple seen with Paget’s disease of the breast were first described by Velpeau in 1856.
  • Paget's disease of the breast was first discovered by James Paget, a British surgeon and physiologist, in 1874.[1]
  • The correlation between intraductal cancer and Paget’s disease of the breast was by Jacobeus in 1904.
  • These findings of breast cance being the underling cause of paget's disease was later supported by Muir and Inglis.
  • The background for the epidermotropic theory that ducts containing carcinoma cells were apparently connected to overlying nipples containing Paget’s cells was then demonstrated by Muir and Inglis.
  • The first case of Paget's disease in a male was described by Elbogen in 1908[2]
  • Extramammary Paget's disease (EMPD) is a histologically identical entity firstdescribed by Crocker in 1889.[3]

References

  1. 1.0 1.1 Lopes Filho, Lauro Lourival; Lopes, Ione Maria Ribeiro Soares; Lopes, Lauro Rodolpho Soares; Enokihara, Milvia M. S. S.; Michalany, Alexandre Osores; Matsunaga, Nobuo (2015). "Mammary and extramammary Paget's disease". Anais Brasileiros de Dermatologia. 90 (2): 225–231. doi:10.1590/abd1806-4841.20153189. ISSN 1806-4841.
  2. Serour, F.; Birkenfeld, S.; Amsterdam, E.; Krispin, M.; Treshchan, O. (1988). "Paget's disease of the male breast". Cancer. 62 (3): 601–605. doi:10.1002/1097-0142(19880801)62:3<601::AID-CNCR2820620326>3.0.CO;2-7. ISSN 0008-543X.
  3. Juang, Guang-Dar; Lin, Meng-Yan; Hwang, Thomas I-Sheng (2011). "Extramammary Paget's disease of the scrotum". Journal of the Chinese Medical Association. 74 (7): 325–328. doi:10.1016/j.jcma.2011.05.010. ISSN 1726-4901.


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