Radiation proctitis risk factors
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief:
Overview
Common risk factors in the development of Radiation proctitis include include dose of radiation, area of the radiation and mode of delivery of the radiation.
Risk Factors
Common Risk Factors
- Common risk factors in the development of radiation proctitis include:[1][2]
- Dose of the radiation: <45 Gy are associated with few long-term radiation side effects. In contrast, doses between 45 and 70 Gy cause more complications, and doses above 70 Gy cause significant and longstanding injury to the surrounding area
- Area of the radiation
- Mode of the delivery of the radiation
Less Common Risk Factors
- Less common risk factors in the development of Radiation proctitis are the diseases that may increases the susceptibility of mucosal injury by radiation are:
- HIV
- Inflammatory bowel disease
- Hx of smoking
- Diabetes Mellitus
- Hypertension
- Hx of atherosclerosis
- Younger age
References
- ↑ Beard CJ, Propert KJ, Rieker PP, Clark JA, Kaplan I, Kantoff PW; et al. (1997). "Complications after treatment with external-beam irradiation in early-stage prostate cancer patients: a prospective multiinstitutional outcomes study". J Clin Oncol. 15 (1): 223–9. doi:10.1200/JCO.1997.15.1.223. PMID 8996146.
- ↑ Coia LR, Myerson RJ, Tepper JE (1995). "Late effects of radiation therapy on the gastrointestinal tract". Int J Radiat Oncol Biol Phys. 31 (5): 1213–36. doi:10.1016/0360-3016(94)00419-L. PMID 7713784.