Uveal melanoma history and symptoms
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Simrat Sarai, M.D. [2]
Overview
A positive history of pre-existing iris nevus which increased in size, eye pain, visual loss, blurred vision, floaters, age between 50_70 years old, male gender, white race, pregnancy, impaired immune system, light colored-irides, sunlight exposure, trauma, and fluorescent lighting exposure is suggestive of uveal melanoma. The most common symptoms of name] include ,eye pain, blurred vision, eye redness, loss of peripheral vision, poor or blurry vision in one eye, a dark spot on the iris, seeing flashing lights, and floaters.
History and Symptoms
- Symptoms of uveal melanoma include eye pain, blurred vision, eye redness, loss of peripheral vision, poor or blurry vision in one eye, a dark spot on the iris, seeing flashing lights, and floaters.
History
Patients with uveal melanoma may have a positive history of:[1][2][3][4][5][6][7][8][9][10]
- Pre-existing iris nevus which increased in size
- Eye pain
- Visual loss
- Blurred vision
- Floaters
- Age between 50_70 years old
- Male gender
- white race
- Pregnancy
- Impaired immune system
- light colored-irides
- Sunlight exposure
- Trauma
- Fluorescent lighting exposure
Common Symptoms
Common symptoms of uveal melanoma include:[11] [12]
- Eye pain
- Blurred vision
- Eye redness
- Loss of peripheral vision
- Poor or blurry vision in one eye
- A dark spot on the iris
- Seeing flashing lights
- Floaters
Less Common Symptoms
Less common symptoms of uveal melanoma include:
References
- ↑ Egan, Kathleen M.; Seddon, Johanna M.; Glynn, Robert J.; Gragoudas, Evangelos S.; Albert, Daniel M. (1988). "Epidemiologic aspects of uveal melanoma". Survey of Ophthalmology. 32 (4): 239–251. doi:10.1016/0039-6257(88)90173-7. ISSN 0039-6257.
- ↑ Uveal melanoma. National Cancer Institute(2015) http://www.cancer.gov/types/eye/hp/intraocular-melanoma-treatment-pdq Accessed on October 24 2015
- ↑ van, J.G.M.; Koopmans, A.E.; Verdijk, R.M.; Naus, N.C.; de, A.; Kilic, E. (2013). "Diagnosis, Histopathologic and Genetic Classification of Uveal Melanoma". doi:10.5772/53631.
- ↑ Reese, Algernon B. (1944). "Pigment Freckles of the Iris (Benign Melanomas): Their Significance in Relation to Malignant Melanoma of the Uvea⋆". American Journal of Ophthalmology. 27 (3): 217–226. doi:10.1016/S0002-9394(44)91382-6. ISSN 0002-9394.
- ↑ Siegel, Ralph (1963). "Malignant Ocular Melanoma During Pregnancy". JAMA: The Journal of the American Medical Association. 185 (6): 542. doi:10.1001/jama.1963.03060060140028. ISSN 0098-7484.
- ↑ Fisher, M.; Kripke, M. (1982). "Suppressor T lymphocytes control the development of primary skin cancers in ultraviolet-irradiated mice". Science. 216 (4550): 1133–1134. doi:10.1126/science.6210958. ISSN 0036-8075.
- ↑ "Risk Factors for Ocular Melanoma: Western Canada Melanoma Study<xref ref-type="fn" rid="FN1">2</xref><xref ref-type="fn" rid="FN2">3</xref>". JNCI: Journal of the National Cancer Institute. 1985. doi:10.1093/jnci/74.4.775. ISSN 1460-2105.
- ↑ Tucker, Margaret A.; Shields, Jerry A.; Hartge, Patricia; Augsburger, James; Hoover, Robert N.; Fraumeni, Joseph F. (1985). "Sunlight Exposure as Risk Factor for Intraocular Malignant Melanoma". New England Journal of Medicine. 313 (13): 789–792. doi:10.1056/NEJM198509263131305. ISSN 0028-4793.
- ↑ Baba, F. E.; Blumenkranz, M. (1986). "Malignant Melanoma at the Site of Penetrating Ocular Trauma". Archives of Ophthalmology. 104 (3): 405–409. doi:10.1001/archopht.1986.01050150105038. ISSN 0003-9950.
- ↑ Beral, Valerie; Shaw, Helen; Evans, Susan; Milton, Gerald (1982). "MALIGNANT MELANOMA AND EXPOSURE TO FLUORESCENT LIGHTING AT WORK". The Lancet. 320 (8293): 290–293. doi:10.1016/S0140-6736(82)90270-7. ISSN 0140-6736.
- ↑ Retinoblastoma. Radiopedia(2015) http://radiopaedia.org/articles/primary-uveal-malignant-melanoma Accessed on October 21, 2015
- ↑ Jovanovic P, Mihajlovic M, Djordjevic-Jocic J, Vlajkovic S, Cekic S, Stefanovic V (2013). "Ocular melanoma: an overview of the current status". Int J Clin Exp Pathol. 6 (7): 1230–44. PMC 3693189. PMID 23826405.