Central pontine myelinolysis primary prevention

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohamadmostafa Jahansouz M.D.[2]

Primary Prevention

The hyponatremia should be corrected at a rate not exceeding 10 mmol/L/24 h or 0.5 mEq/L/h; or 18 mEq/L/48hrs to minimize the risk of this condition developing from the overly rapid reversal of hyponatremia, thus avoiding demyelination. Effective measures for the primary prevention of [disease name] include:

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