Endocardial cushion defect screening

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aditya Ganti M.B.B.S. [2]

Overview

Routine fetal ultrasound during prenatal care can detect endocardial cushion defects. Diagnostic findings on fetal ultrasound suggestive of endocardial cushion defect include large defect at the crux of the heart that involves the atrial and ventricular septa and a large common AV valve.

Screening

  • During prenatal care routine fetal ultrasound can make an early in-utero diagnosis of endocardial cushion defect.[1]
  • Diagnostic findings on fetal ultrasound suggestive of endocardial cushion defect include:
    • Large defect at the crux of the heart that involves the atrial and ventricular septa,
    • Large common AV valve
  • When abnormalities are detected on fetal ultrasound it should be followed by a fetal echocardiography for confirmation due to poor sensitivity of ultrasound.

References

  1. Machado MV, Crawford DC, Anderson RH, Allan LD (March 1988). "Atrioventricular septal defect in prenatal life". Br Heart J. 59 (3): 352–5. doi:10.1136/hrt.59.3.352. PMC 1216470. PMID 3355725.

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