Heart transplantation immunosuppressive therapy

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Editor(s)-in-Chief: C. Michael Gibson, M.S., M.D.; Associate Editor-In-Chief: Cafer Zorkun, M.D., Ph.D. [1]

Immunosuppressive Therapy

Cyclosporine A

Cyclosporine Induced Hypertension

Hypertension occurs in 60% of patients on cyclosporine. The etiology is thought to be due to vasoconstriction. There is a loss of circadian rhythm in blood pressure. Verapamil, cardizem and nicardipine increase cyclosporine concentrations.