Palpitation natural history, complications and prognosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Akash Daswaney, M.B.B.S[2]

Overview

If left untreated, [#]% of patients with [disease name] may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3].

OR

Common complications of [disease name] include [complication 1], [complication 2], and [complication 3].

OR

Prognosis is generally excellent/good/poor, and the 1/5/10-year mortality/survival rate of patients with [disease name] is approximately [#]%.

Natural History, Complications, and Prognosis

Natural History

  • Palpitations may present during one's childhood or in the elderly as a flip flopping, fluttering, pounding or thud like sensation in one particular area of the chest or all over the precordium.
  • It may be regular or irregular, sustained or momentary and may be associated with symptoms such as chest pain, breathlessness, pedal edema, polyuria or signs of haemodynamic instability.

Complications and Prognosis

  • Patients presenting with palpitations generally have a good prognosis (especially in the absence of a cardiac condition), but data regarding this is scarce. [1]
  • However, associated symptoms play a major role in whether one should ‘worry’ or not.
    • Positive ECG findings, frequent or persistent palpitations, positive family history (sudden cardiac death, myopathy or cardiac condition) and symptoms such as presyncope, syncope, dyspnea and chest pain would require specialist referral.[2]
  • In a study conducted by Weber and Kapoor, a one year mortality rate of 1.6% was noted despite a high incidence of cardiac conditions. [3]
    • In the same study, a large number of patients experienced a significant impact on their quality of life in terms of their work capacity, and ability to perform household chores
  • Barsky et al confirmed these findings when they noted a low one year mortality rate but increased incidence of anxiety in individuals with palpitations, increased frequency of visits to the emergency department and therefore a decrease in the patient’s quality of life.• [4]
  • Other complications that arise due to the underlying arrhythmia include hypotension, congestive heart failure ,acute pulmonary edema and sudden cardiac death.


References

  1. McLellan AJ, Kalman JM (2019). "Approach to palpitations". Aust J Gen Pract. 48 (4): 204–209. doi:10.31128/AJGP-12-17-4436. PMID 31256490.
  2. Raviele A, Giada F, Bergfeldt L, Blanc JJ, Blomstrom-Lundqvist C, Mont L; et al. (2011). "Management of patients with palpitations: a position paper from the European Heart Rhythm Association". Europace. 13 (7): 920–34. doi:10.1093/europace/eur130. PMID 21697315.
  3. Weber BE, Kapoor WN (1996). "Evaluation and outcomes of patients with palpitations". Am J Med. 100 (2): 138–48. doi:10.1016/s0002-9343(97)89451-x. PMID 8629647.
  4. Barsky AJ (2001). "Palpitations, arrhythmias, and awareness of cardiac activity". Ann Intern Med. 134 (9 Pt 2): 832–7. doi:10.7326/0003-4819-134-9_part_2-200105011-00006. PMID 11346318.

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