Wolff-Parkinson-White syndrome epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Cafer Zorkun, M.D., Ph.D. [2]

Epidemiology and Demographics

• The prevalence of WPW syndrome is approximately 1-3 per 1000 individuals worldwide.
• The Prevalence of WPW syndrome in the first relative of patients is approximately 5-6 per 1000 people.
• The incidence of tachyarrhythmia was estimated to be 1% per year in patients with WPW pattern.
• The prevalence of ventricular fibrillation and sudden cardiac death in asymptomatic WPW syndrome was estimated to be 0.1% individuals worldwild.
• The prevalence of ventricular fibrillation and sudden cardiac death in WPW syndrome with reciprocal tachycardia was estimated to be 1% individuals worldwild.
• The prevalence of ventricular fibrillation and sudden cardiac death in WPW syndrome with rapid atrial fibrillation was estimated to be 5.6% individuals worldwild.
• WPW syndrome is more commonly observed among young patients. In one study WPW syndrome was observed in 7% individuals over 60-year-old.

• men are more commonly affected with [WPW syndrome] than women.
• The men to women ratio is approximately 2 to 1.
• There is no racial predilection for WPW syndrome.

• The incidence of WPW is higher in men than in women in a ratio of approximately 2:1. Also, atrial fibrillation and ventricular fibrillation are more common in men than in women with WPW.

of asymptomatic patients with WPW in 1% in those with reciprocal tachycardias and in 5.6% of the patients with atrial fibrillation

In [year], the incidence of [disease name] was estimated to be [number or range] cases per 100,000 individuals in [location].

• Age

   Patients of all age groups may develop [disease name].
   [Disease name] is more commonly observed among patients aged [age range] years old.
   

Gender

   [Disease name] affects men and women equally.
   [Gender 1] are more commonly affected with [disease name] than [gender 2].
   The [gender 1] to [Gender 2] ratio is approximately [number > 1] to 1.

Race

   There is no racial predilection for [disease name].
   [Disease name] usually affects individuals of the [race 1] race.
   [Race 2] individuals are less likely to develop [disease name].

The same happens in patients with atrial fibrillation, observed in 5% of the patients with WPW syndrome; this arrhythmia may provoke multiform ventricular tachycardia, ventricular fibrillation and sudden death. Sudden death occurs in 0.1% of asymptomatic patients with WPW in 1% in those with reciprocal tachycardias and in 5.6% of the patients with atrial fibrillation and R-R intervals of 250 mseg of less.

• Estimated prevalence of WPW syndrome is 1 - 3 per 1000 people in the entire world.
• Prevalence increases in first degree relatives in which it can get as high as 5-6 per 1000 people.
• The incidence of tachyarrhythmias is not well established in patients who present WPW pattern. It has been reported that the incidence of tachyarrhytmias is approximately 1% per year in patients with WPW pattern.
• The incidence of sudden cardiac death in patients with Wolff-Parkinson-White pattern is not high. A serious of studies have been performed and found a that this events appear in a range of 0.7 tp 4.5 per 1000 patient-years.
• Incidence of WPW is higher in men than in women in a ratio of approximately 2:1. Also, atrial fibrillation and ventricular fibrillation are more common in men than in women with WPW.
• Incidence of Orthodromic AVRT is more common in women than in men.
• The presentation of symptoms in patients without heart structural abnormalities has been found to be age dependent.
• The frequency of Supraventricular tachycardias (SVT) usually decrease during the first year in more than 90% of the patients.
• In 30% of the patients, tachycardias recur during childhood at a mean age of 7 to 8 years of age.
• When patients with WPW present persistent symptomatic tachycardias over 5 years of age, they usually continue presenting SVT episodes for more than a decade later in 75% of the cases.
• The occurrence of atrial fibrillation in patients with WPW ha been estimated in between 10% to 30%.

* There is no racial predilection for WPW syndrome.