Tremor natural history, complications and prognosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Zehra Malik, M.B.B.S [2]

Overview

Essential tremor and Parkinson's disease worsens with time, treatment helps minimizing symptoms. Physiologic tremor and drug induced tremor do not worsen with time and can be controlled. Tremors may be mild, or can be very disabling for some patients. Patients with tremors have shown to have decrease quality of life physically and mentally as compared to healthy population.

Natural History

Tremor is not a life-threating condition. However, if not symptomatically treated it can cause severe physical, mental and social disabilities depending on the intensity of tremors.
Essential tremor and Parkinson's disease generally worsen with time. Physiologic tremor and drug induced tremor do not worsen with time and can be controlled.^[1]

Complications

Reduces quality of life
Can cause social disability.
May limit their physical activity
Patients with essential tremor have shown to have decrease quality of life physically and mentally as compared to healthy population. ^[2]
Depression

Prognosis

Tremors may be mild, or can be very disabling for some patients.
Essential tremor is a gradually progressing disease.The symptoms usually worsen with age.^[3]
It has been observed that patients suffering from essential tremors are more likely to develop other forms of neurodegenerative disorders including, Parkinson's disease, Alzheimer's disease as compared to average population especially if age of onset is after 65 years.^[4]
Physiologic and drug-induced tremor with time do not worsen, They can be completely controlled by eliminating the causative drug for drug-induced tremor or controlling the enhancing factors for physiologic tremors.^[1]

↑ ^1.0 ^1.1 Puschmann, Andreas; Wszolek, Zbigniew (2011). "Diagnosis and Treatment of Common Forms of Tremor". Seminars in Neurology. 31 (01): 065–077. doi:10.1055/s-0031-1271312. ISSN 0271-8235.
↑ Lorenz D, Schwieger D, Moises H, Deuschl G (2006). "Quality of life and personality in essential tremor patients". Mov Disord. 21 (8): 1114–8. doi:10.1002/mds.20884. PMID 16622851.
↑ Elble, Rodger J. (2013). "What is Essential Tremor?". Current Neurology and Neuroscience Reports. 13 (6). doi:10.1007/s11910-013-0353-4. ISSN 1528-4042.
↑ Rajput AH, Adler CH, Shill HA, Rajput A (2012). "Essential tremor is not a neurodegenerative disease". Neurodegener Dis Manag. 2 (3): 259–268. doi:10.2217/nmt.12.23. PMC 3478956. PMID 23105950.