Ventricular tachycardia laboratory findings
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Ventricular tachycardia Microchapters |
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Differentiating Ventricular Tachycardia from other Disorders |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Sara Zand, M.D.[2]
Overview
Serial cardiac enzymes, serum electrolytes as well as calcium, magnesium and phosphate levels, should be obtained. A toxicology screen should also be obtained to assess for illicit drugs as the cause of the VT, as well as levels of medications that may have caused the VT.
Laboratory Findings
Common laboratory findings predicting sudden cardiac arrest and ventricular tachycardia include:
- Elevated level of Natriuretic peptides—B-type (BNP) or N-terminal pro-BNP as the marker of myocardial stress and fibrosis in heart failure disease[1]
- Highly sensitive troponin T indicating cardiomyocyte injury[2]
- Electrolytes abnormality such as hypokalemia, hypomagnesemia relation QT prolongation and torsades de pointes[3]
- Tricyclic antidepressant poisoning associated with QT prolongation [5]
- Cocaine toxicology screening[6]
| Laboratory Pearls for Ventricular Tachycardia | |
|---|---|
| Electrolytes | Hypokalemia and hypomagnesemia frequently associated with torsades de pointes |
| Troponin I | Elevated in myocardial infarction |
| Creatine-kinase MB | Elevated in myocardial infarction |
References
- ↑ Ahmad, Tariq; Fiuzat, Mona; Neely, Benjamin; Neely, Megan L.; Pencina, Michael J.; Kraus, William E.; Zannad, Faiez; Whellan, David J.; Donahue, Mark P.; Piña, Ileana L.; Adams, Kirkwood F.; Kitzman, Dalane W.; O'Connor, Christopher M.; Felker, G. Michael (2014). "Biomarkers of Myocardial Stress and Fibrosis as Predictors of Mode of Death in Patients With Chronic Heart Failure". JACC: Heart Failure. 2 (3): 260–268. doi:10.1016/j.jchf.2013.12.004. ISSN 2213-1779.
- ↑ Hussein, Ayman A.; Gottdiener, John S.; Bartz, Traci M.; Sotoodehnia, Nona; deFilippi, Christopher; Dickfeld, Timm; Deo, Rajat; Siscovick, David; Stein, Phyllis K.; Lloyd-Jones, Donald (2013). "Cardiomyocyte Injury Assessed by a Highly Sensitive Troponin Assay and Sudden Cardiac Death in the Community". Journal of the American College of Cardiology. 62 (22): 2112–2120. doi:10.1016/j.jacc.2013.07.049. ISSN 0735-1097.
- ↑ Laslett, David B.; Cooper, Joshua M.; Greenberg, Richard M.; Yesenosky, George A.; Basil, Anuj; Gangireddy, Chethan; Whitman, Isaac R. (2020). "Electrolyte Abnormalities in Patients Presenting With Ventricular Arrhythmia (from the LYTE-VT Study)". The American Journal of Cardiology. 129: 36–41. doi:10.1016/j.amjcard.2020.04.051. ISSN 0002-9149.
- ↑ Menduiña, Manuel J.; Candel, José M.; Alaminos, Pilar; Gómez, Francisco J.; Vilchez, José (2005). "Bidirectional Ventricular Tachycardia Due to Digitalis Poisoning". Revista Española de Cardiología (English Edition). 58 (8): 991–993. doi:10.1016/S1885-5857(06)60385-X. ISSN 1885-5857.
- ↑ Sabah K, Chowdhury AW, Islam MS, Saha BP, Kabir SR, Kawser S (July 2017). "Amitriptyline-induced ventricular tachycardia: a case report". BMC Res Notes. 10 (1): 286. doi:10.1186/s13104-017-2615-8. PMC 5513042. PMID 28709467. Vancouver style error: initials (help)
- ↑ Hoffman, Robert S. (2010). "Treatment of patients with cocaine-induced arrhythmias: bringing the bench to the bedside". British Journal of Clinical Pharmacology. 69 (5): 448–457. doi:10.1111/j.1365-2125.2010.03632.x. ISSN 0306-5251.