Eczema future or investigational therapies
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1], Associate Editor(s)-in-Chief: Edzel Lorraine Co, D.M.D., M.D.
Overview
More emphasis on genetic studies will be given in the future to unfold the remaining majority of unexplained heritability in eczema. However, the challenge still lies in the economical and computational requirements. [1]
Eczema Future or Investigational Therapies
- More emphasis on genetic studies will be given in the future to unfold the remaining majority of unexplained heritability in eczema. However, the challenge still lies in the economical and computational requirements.
- These genetic discoveries can be applied to the development of new drugs that can target the molecular and physiological causes of the disease, making an era of "personalized medicine". [2]
References
- ↑ Brown SJ, Kroboth K, Sandilands A, Campbell LE, Pohler E, Kezic S; et al. (2012). "Intragenic copy number variation within filaggrin contributes to the risk of atopic dermatitis with a dose-dependent effect". J Invest Dermatol. 132 (1): 98–104. doi:10.1038/jid.2011.342. PMC 3236450. PMID 22071473.
- ↑ Dugger SA, Platt A, Goldstein DB (2018). "Drug development in the era of precision medicine". Nat Rev Drug Discov. 17 (3): 183–196. doi:10.1038/nrd.2017.226. PMC 6287751. PMID 29217837.