Systemic lupus erythematosus risk factors

Systemic lupus erythematosus Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Raviteja Guddeti, M.B.B.S. [2]

Overview

The underlying cause of this autoimmune disease is not clear. Clinical data show the onset of systemic lupus erythematosus is associated with the following factors:

• Female: SLE affects nine times as many women as men.
• Age: From 10 to 50
• Race: African Americans and Asians are affected more often than people from other races.
• Drugs, such as chlorpromazine, hydralazine, isoniazid, methyldopa, penicillamine, procainamide, quinidine and sulfasalazine.