Disseminated intravascular coagulation laboratory findings
Disseminated intravascular coagulation Microchapters |
Differentiating Disseminated intravascular coagulation from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Laboratory findings
The peripheral smear will reveal schistocytes and RBC (red blood cell) fragments in ~ 50%, and the absence of schistocytes does not rule out DIC. Most patients will have a mild reticulocytosis and leukocytosis, as well as thrombocytopenia with an increased population of young platelets (due to increased destruction and turnover). Pathologically, early signs include platelet-rich microthrombi, which are then replaced by fibrin-rich microthrombi.