Hypertrophic cardiomyopathy risk factors for sudden death
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Patients with hypertrophic cardiomyopathy are increased risk of sudden cardiac death. Identification of those patients at an increased risk can facilitate early treatment with an automatic implantable cardiac defibrillator.
Risk Factors for Sudden Death in Patients with Hypertrophic Cardiomyopathy
Risk factors for sudden death in individuals with HCM include[1]:
- A young age at first diagnosis (age < 30 years)
- An episode of aborted sudden death
- A family history of HCM with sudden death of relatives
- Specific mutations in the genes encoding for troponin T and myosin
- Sustained supraventricular or ventricular tachycardia
- Ventricular septal wall thickness over 3 cm
- A hypotensive response to exercise
- Recurrent syncope (especially in children)
- Bradyarrhythmias (slow rhythms of the heart).
2011 ACCF/AHA Guideline Recommendations: SCD Risk Stratification (DO NOT EDIT)
References
- ↑ Maron BJ, Cecchi F, McKenna WJ (1994). "Risk factors and stratification for sudden cardiac death in patients with hypertrophic cardiomyopathy". Br Heart J. 72 (6 Suppl): S13–8. doi:10.1136/hrt.72.6_Suppl.S13. PMC 1025670. PMID 7873317. Unknown parameter
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ignored (help) and the Task Force on Sudden Cardiac Death of the European Society of Cardiology link Note: Guideline withdraw