Acute liver failure historical perspective
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Historical Perspective
- To date no universally accepted nomenclature has been adopted.
- Trey and Davidson introduced the term fulminant hepatic failure in 1970 to describe "potentially reversible condition, the consequence of severe liver injury, with an onset of encephalopathy within 8 weeks of the appearance of the first symptoms and in the absence of pre-existing liver disease"[1].
- Later it was suggested that the term fulminant should be confined to patients who develop jaundice to encephalopathy within 2 weeks. Terms subfulminant hepatic failure and late onset hepatic failure were coined for onset between 2 weeks to 3 months and for 8 weeks to 24 weeks respectively[2][3].
- The umbrella term of acute liver failure was proposed by Kings college group which has been adopted in this article. Paradoxically in this classification the best prognosis is in the hyperacute group[4].
References
- ↑ Trey C, Davidson CS (1970). "The management of fulminant hepatic failure". Progress in liver diseases. 3: 282–98. PMID 4908702.
- ↑ Bernuau J, Goudeau A, Poynard T; et al. (1986). "Multivariate analysis of prognostic factors in fulminant hepatitis B". Hepatology. 6 (4): 648–51. PMID 3732998.
- ↑ Gimson AE, O'Grady J, Ede RJ, Portmann B, Williams R (1986). "Late onset hepatic failure: clinical, serological and histological features". Hepatology. 6 (2): 288–94. PMID 3082735.
- ↑ Sass DA, Shakil AO (2005). "Fulminant hepatic failure". Liver Transpl. 11 (6): 594–605. doi:10.1002/lt.20435. PMID 15915484.