Congenital syphilis screening

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aditya Govindavarjhulla, M.B.B.S. [2]

Overview

Routine screening of newborn serum or umbilical cord blood is not recommended. Serologic testing of the mother’s serum is preferred rather than testing the infant’s serum.

Screening

  • Newborn serum is not used for serologic tests instead mother's serum is prefered. [1]
  • The serologic tests performed on infant serum can be nonreactive if the mother’s serologic test result is of low titer or the mother was infected late in pregnancy.
  • Screening can be performed using either a nontreponemal or treponemal test. If either screening test is positive, testing must be performed immediately using the other complimentary test (i.e., nontreponemal test followed by treponemal test or vice-versa).
  • No infant or mother should leave the hospital unless maternal serologic status has been documented at least once during pregnancy; in communities and populations in which the risk for congenital syphilis is high, documentation should also occur at delivery.

References

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  1. "CDC - Diseases Characterized by Genital, Anal, or Perianal Ulcers - 2010 STD Treatment Guidelines". Retrieved 2012-12-20.