TIMI thrombus grade 5

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

In PERFUSE Grade 5 thrombus, a recent total occlusion is present. [1]

The characteristics of a recent total occlusion are:

  • There is often a beak like appearance of the occlusion. Chronic occlusions tend to have a more abrupt or straight appearance.
  • The clot has not propagated backward to the most distal branch.
  • Some collaterals may be present, but usually there are not extensive collaterals.

Example

Shown below are an animated image and a static image depicting PERFUSE grade 5 thrombus in the RCA. Outlined in yellow in the image on the right is the beak like appearance of the occlusion.

[[Image:|300px|PERFUSE grade 5 thrombus in the RCA]] [[Image:|300px|PERFUSE grade 5 thrombus in the RCA. Note the beak like appearance of the thrombus which is outlines in yellow.]]

References

  1. Gibson CM, de Lemos JA, Murphy SA, Marble SJ, McCabe CH, Cannon CP; et al. (2001). "Combination therapy with abciximab reduces angiographically evident thrombus in acute myocardial infarction: a TIMI 14 substudy". Circulation. 103 (21): 2550–4. PMID 11382722.