Renal artery stenosis overview
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Renal artery stenosis is defined as the unilateral or bilateral progressive narrowing of the renal arteries or their branches of more than 50% in diameter.[1] It is a heterogeneous group of diseases that most commonly include: fibromuscular dysplasia (FMD) and atherosclerotic renal artery stenosis (ARAS). Although renal artery stenosis may be an isolated asymptomatic condition, it may commonly lead to secondary hypertension and ischemic nephropathy, and chronic renal insufficiency.[2][3]
Normal 0 false false false EN-US JA X-NONE Approximately 90% of renal artery stenosis cases occur due to progressive atherosclerosis. The ostium and proximal third of the renal arteries are the most commonly involved regions in atherosclerosis. Nonetheless, segmental and diffuse atherosclerosis may still be seen in the minority of patients, especially in context of chronic kidney disease and poor renal survival.
References
- ↑ Simon G (2000). "What is critical renal artery stenosis? Implications for treatment". Am J Hypertens. 13 (11): 1189–93. PMID 11078179.
- ↑ Dworkin LD, Cooper CJ (2009). "Clinical practice. Renal-artery stenosis". N Engl J Med. 361 (20): 1972–8. doi:10.1056/NEJMcp0809200. PMID 19907044.
- ↑ Zierler RE, Bergelin RO, Isaacson JA, Strandness DE (1994). "Natural history of atherosclerotic renal artery stenosis: a prospective study with duplex ultrasonography". J Vasc Surg. 19 (2): 250–7, discussion 257-8. PMID 8114186.