TIMI flow grade 1
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Definition
Penetration without perfusion. Contrast material passes beyond the area of obstruction but fails to opacify the entire coronary bed distal to the obstruction for the duration of the cineangiographic filming sequence.[1] [2] [3]
This category is subdivided into:
- 1.0: dye minimally leaks past the area of obstruction.
- 1.5: dye leaks well past the area of obstruction but fails to opacify the entire coronary bed prior to the end of cinefilming. Had cinefilming continued longer, dye may have reached the landmark.
Example
TIMI Flow Grade 1 - Left Anterior Descending Artery
TIMI Flow Grade 1.5 - Left Anterior Descending Artery
Additional Examples
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References
- ↑ Gibson, CM; Ryan, K; Sparano, A; Rizzo, M; Moynihan, J; Kelley, M; Marble, SJ; Dodge, JT; Antman, EM. Methodologic drift in the assessment of TIMI grade 3 flow and its implications with respect to the reporting of angiographic trial results. Am Heart J. 1999;137:1179–1184. PMID 10347349
- ↑ Gibson CM, Cannon CP, Daley WL, Dodge JT Jr, Alexander B Jr, Marble SJ, McCabe CH, Raymond L, Fortin T, Poole WK, Braunwald E. TIMI frame count: a quantitative method of assessing coronary artery flow. Circulation. 1996 Mar 1;93(5):879-88. PMID 8598078
- ↑ Gibson CM, Murphy S, Menown IB, Sequeira RF, Greene R, Van de Werf F, Schweiger MJ, Ghali M, Frey MJ, Ryan KA, Marble SJ, Giugliano RP, Antman EM, Cannon CP, Braunwald E. Determinants of coronary blood flow after thrombolytic administration. TIMI Study Group. Thrombolysis in Myocardial Infarction. J Am Coll Cardiol. 1999 Nov 1;34(5):1403-12. PMID 10551685