Focal segmental glomerulosclerosis historical perspective
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It is believed that Theodor Fahr, a German pathologist, first was first to describe "progressive lipoid nephrosis" in 1925 and to draw an illustration of focal segmental glomerulosclerosis (FSGS).[1] At the time, he referred to it as "lipoid nephrosis with degeneration", showing a clear association to minimal change disease. FSGS was then described in 1957 by Dr. Arnold Rich, a pathologist at Johns Hopkins University.[2] His original article "A hitherto undescribed vulnerability of the juxtamedullary glomeruli in lipoid nephrosis" was originally published in "Bulletin of the Johns Hopkins Hospital".[2] In his original description, he noted the presence of segmental sclerosis in juxtamedullary glomeruli of autopsies of uremic children with nephrosis.[2]
References
- ↑ Fahr, T (1925). Pathologische anatomie des morbus brightii. In: Fahr T, Gruber GB, Koch M, et al. eds. Harnorgane Männliche Geschlechtsorgane. Vienna: Springer. pp. 156–472.
- ↑ 2.0 2.1 2.2 RICH AR (1957). "A hitherto undescribed vulnerability of the juxtamedullary glomeruli in lipoid nephrosis". Bull Johns Hopkins Hosp. 100 (4): 173–86. PMID 13426687.