Cefpirome indications

Cefpirome
CEFROM® Package Insert
Composition
Properties
Indications
Microbiology
Contraindications
Warnings and Precautions
Adverse Reactions
Drug Interactions
Dosage and Administration
How Supplied

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Indications

Infections caused by CEFROM-sensitive organisms:

• Lower respiratory tract infections

• Complicated upper and lower urinary tract infections

• Bacteremia/septicemia

• Infections in neutropenic and immunocompromised patients

• Skin and soft tissue infections

• Severe infections in intensive care patients

Infections caused by the following pathogens have been successfully treated in clinical trials:

Gram-Positive Organisms

• Staphylococcus aureus and coagulative-negative staphylococcus spp.

• Staphylococcus epidermidis

• Staphylococcus hominis

• Staphylococcus saprophyticus

• Staphylococcus warneri

• Hemolytic and non-hemolytic streptococci

• Streptococcus pyogenes (Group A)

• Streptococci of groups B and F

• Streptococcus pneumoniae

• Streptococcus agalactiae

• Streptococcus of viridans groups

• Enterococcus faecalis

• Corynebacterium spp.

Gram-negative organisms

• Escherichia coli

• Enterobacter spp.

• Indole-positive and indole-negative Klebsiella spp. and Proteus spp.

• Morganella morganii

• Providencia spp.

• Citrobacter spp.

• Salmonella spp.

• Hafnia alvei

• Serratia marcescens

• Pasteurella multocida

• Haemophilus influenzae and other Haemophilus species

• Moraxella catarrhalis

• Neisseria spp.

• Alcaligenes spp.

• Pseudomonas aeruginosa and other Pseudomonas species

• Acinetobacter calcoaceticus

• Bacteroides spp.

In Vitro Sensitivity

Gram positive organisms

• Staphylococcus aureus

• Coagulase-neqative Staphylococcus spp.

• Streptococcus Group A, B, C, F, and G

• Streptococcus mitis

• Streptococcus sanguis

• Streptococcus viridans

• Streptococcus pneumoniae

• Propionibacterium acnes

• Peptostreptococcus anaerobius

• Corynebacterium diphtheriae

• Corynebacterium pyogenes

Gram-negative organisms

• Citrobacter spp.

• Escherichia coli

• Salmonella spp.

• Shigella spp.

• Klebsiella spp.

• Enterobacter spp.

• Hafnia alvei

• Serratia spp.

• Proteus mirabilis

• Proteus vulgaris

• Proteus rettgeri

• Morganella morganii

• Providencia spp.

• Yersinia enlerocolitica

• Pasteurella multocida

• Haemophilus influenzae

• Haemophilus ducreyi

• Moraxella catarrhalis

• Neisseria meningitidis

• Neisseria gonorrhoeae

• Aeromonas hydrophilia

Most strains of the following species showing in vitro sensitivity

Gram-positive organisms

• Enterococcus faecalis

• Clostridium spp.

Gram-Negative Organisms

• Pseudomonas aeruginosa

• Pseudomonas spp.

• Acinetobacter spp.

• Bacteroides fragilis

Most strains of the following species are resistant in vitro

Gram-Positive Organisms

• Staphylococcus spp. (methicillin-resistanl strains)

• Enterococcus faecium

• Listeria monocytogenes

• Clostridium difficile

Gram-Negative Organisms

• Xanthomonas maltophilia

• Fusobacterium varium

• Bacteroides fragilis (beta lactamase-producing strains)