Creutzfeldt-Jakob disease laboratory findings

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

The diagnosis of CJD is suspected when there are typical clinical symptoms and signs such as rapidly progressing dementia with myoclonus. Analysis of CSF for 14-3-3 protein is done to establish probable diagnosis. Positive 14-3-3 protein in CSF analysis makes the diagnosis of CJD probable but it is not diagnostic of CJD.

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